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Sou-Pan Wu, MD

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Internal Medicine – Rheumatology, Board Certified Rheumatology Fellowship

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Practice Overview

Over the past two decades since starting his practice, advances in our understanding of rheumatic diseases have evolved greatly. These include not only the discovery of new diseases, uncovering new insights into old diseases, but also progress in treatments options as well.  Diseases once thought to be untreatable and/or life threatening are now controlled with the use of powerful biologics and immunomodulating agents allowing patients to live longer and with improved quality of life.  However, with such an ever-expanding knowledge base comes the challenges of increasing patient management complexities. These may include issues such as side effects of new medications, appropriateness of newer diagnostic modalities, and or navigating through the maze of health care coverages for the different medications which are often quite expensive. These are all difficult and potentially frightening for a patient who is diagnosed with a chronic rheumatologic disease, especially when facing unexpected events like the Covid-19 pandemic while on immunosuppressive medications.  The prognosis and outcome often then depend on the trust and cooperation between the patient and the physician. Dr. Wu strives to provide the best care that he can by being thorough, paying attention to details, practicing evidence-based medicine, and staying up to date.

Sou-Pan Wu, MD graduated from Northwestern University in Evanston, Illinois, and attended University of Illinois at Urbana-Champaign and obtained his Master of Science (MS) in Electrical Engineering. Later he attended Indiana University School of Medicine in Indianapolis, Indiana, then completed his residency at the University of Wisconsin, Madison, and finished his Rheumatology Fellowship at Yale University in New Havens, Connecticut. Dr. Wu is currently a Clinical Assistant Professor at the University of Minnesota and has helped train many current rheumatologists in practice in the Twin Cities. He is also a member of the American College of Rheumatology.

Outside of work, Dr. Wu enjoys playing Weiqi (Go), traveling, and trying out new foods.

Clinical Interest

Rheumatology, including inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis), ankylosing spondylitis, vasculitis, crystalline disease (gout), connective tissue diseases (lupus), and Sjogren’s syndrome

Dr. Wu does not provide management of chronic pain, chronic lyme disease, long COVID-19, Ehlers-Danlos syndrome, hypermobility syndromes, chronic fatigue syndrome (myalgic encephalomyelitis), non-inflammatory spine problems (degenerative arthritis of the cervical or lumbar spine), spinal stenosis, degenerative disc diseases, chronic hives.

Dr. Wu can help establish the diagnosis of fibromyalgia and osteoarthritis but does not manage these conditions long term.


Board Certified, American Board of Internal Medicine – Rheumatology

Rheumatology Fellowship, Yale University, New Havens, CT

University of Wisconsin, Madison, WI

Medical Degree
Indiana University School of Medicine

Hospital & Surgery Center Affiliations

Regions Hospital in St. Paul, MN

Professional Affiliations

American College of Rheumatology,
Christian Medical Dental Society

Achievements & Awards

Eta Kappa Nu Electrical Engineering Honors Society (1987 – 1991)
Tau Beta Pi Engineering Honors Society (1987 – 1991)
National Merit Scholar (1987 – 1991)
Dean’s Letter Various Terms (1987 – 1991)
Recipient of NIH Clinical Research Loan Repayment Program (2002 – 2004)
ACR/REF Fellowship Training Award Fellow (2002 – 2004)
ACR Physician Scientist Development Award (2004 – 2005)


Clinical Assistant Professor, University of Minnesota


Samantha R.
Care Coordinator

Patient Testimonials

March 8, 2024

Gary W.

Dr. Wu has treated me for 10 years and has saved my life multiple times when other doctors have missed diagnosed or not diagnosed problems that could have been fatal. I suffer from multiple chronic autoimmune diseases. Dr. Wu has worked with drug manufacturers and insurance companies to approve multiple biologic medicines at once that have never been approved together before. His tenacity to do what is needed for his patients is unbelievable. When he sees the opportunity for his patients to have a better chance at quality of life, he is willing to fight on their behalf.

October 19, 2023

Deborah M.

I have been under Dr. Wu’s care for one year. I walked in with painful joints and he diagnosed me with Rheumatoid Arthritis. He prescribed the proper medications to get me back to functioning like my normal self. He and his care coordinator, Samantha, are always available to take and respond to message, or adjust medications as needed. I would never leave this area because I don’t believe there is another doctor anywhere that could fill Dr. Wu’s shoes.

Deb M Rheumatology

September 28, 2023

Dawn Q.

I’ve only seen Dr. Wu twice and he got to the root of my disease immediately. I have a deep respect for him and I am honored that he is my physician. I would recommend him to anybody that has rheumatoid issues. Dr. Wu is a healer.

July 18, 2023

John S.

I am a new patient to TCO and the Rheumatology group. I have had a wonderful experience with everyone, including Dr. Wu and his team. The staff have been incredibly supportive, helpful and patient as I have begun my new journey with TCO. It’s refreshing to have everyone so willing to help and take the time for a new patient. Thank you so much!

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